Frequently Asked Questions

Answers to all of our frequently asked questions about treatments, ketamine therapy, and our clinical research at IIT.

Treatment FAQs

We offer several options for healing with psychedelics, including:

  • IV Ketamine Infusions (1-hour for mental health, 2-hour for chronic pain)
  • Intramuscular (IM) Ketamine, without a therapist
  • Ketamine-Assisted Psychotherapy (KAP) IM ketamine, with a therapist
  • Spravato® (esketamine) nasal spray

All treatments are provided in a calm, supportive medical setting. Our team of physicians, nurses, and therapists ensures your safety and comfort every step of the way.

We use a bio-psycho-spiritual model that treats the whole person — not just symptoms —
integrating:

  • Physiological health: nutrition, exercise, sleep, stress reduction
  • Psychological care: medication support and psychotherapy
  • Spiritual growth: purpose, meaning, and personal development

Rather than offering medication alone, we combine medical treatment, structured
integration support, and lifestyle foundations designed to help changes translate into
everyday life.

IIT is the only psychedelic medicine clinical research site in Minnesota and one of the
largest in the Midwest, helping shape the future of the field while offering patients access
to emerging innovation.

Click here to learn more about IIT’s clinical trials

IV Ketamine (typical starting approach)
Many patients begin with an induction series of six treatments, commonly scheduled:

  • Twice weekly for 3 weeks
  • Once weekly for 6 weeks

Ketamine-Assisted Psychotherapy (KAP)

  • It is commonly recommended to complete three KAP sessions spaced 2–4 weeks apart.

Spravato® (esketamine)

  • The typical induction phase includes two treatments per week for four weeks, following FDA-guided protocols

Medical follow-up
Medical follow-up visits occur throughout your treatment series and again at completion to evaluate progress and next steps.

Integration support

  • Patients receiving IV ketamine, IM ketamine (without a therapist present), or Spravato® often benefit from meeting with an integration therapist within 1–2 days following treatment
  • Patients receiving Ketamine-Assisted Psychotherapy typically complete 1–2 preparation sessions prior to treatment and 1–2 integration sessions afterward

Integration therapy is optional but highly recommended. Many patients choose 1–2 therapy sessions before and after treatment to process insights and anchor changes.

Yes—Spravato® is typically covered by most insurance plans. IIT is in-network with the following commercial plans:

  • Aetna
  • Allina Health
  • Blue Cross and Blue Shield
  • Cigna
  • HealthPartners
  • Medica
  • Tricare

IV ketamine, IM ketamine, and Ketamine-Assisted Psychotherapy (KAP) are considered
self-pay treatments. However, some insurance plans may cover the medical management
portion of these services. Currently, this may include:

  • Allina Health
  • Cigna
  • HealthPartners
  • Medica

Patients are responsible for confirming coverage with their insurance plan prior to their
first ketamine treatment and should request a reference number from that conversation.
Please bring this reference number to your medical evaluation so it can be documented in
your chart.

All ketamine treatments (except Spravato®) include an additional out-of-pocket cost
for noncovered services. The amount varies depending on the type of treatment.

Payment for non-covered services is collected at check-in. Any insurance responsibility
will be billed through the patient portal after claims have been processed.

We accept cash, check, credit and debit cards, HSA/FSA, and CareCredit, which offers
flexible payment options.

We recognize that investing in your health and healing is an important decision. Our goal is to provide transparency so you can make informed, empowered choices about your care.

Typical self-pay investment amounts include:

  • Ketamine Treatment (IV or IM): $500 per treatment
  • Ketamine-Assisted Psychotherapy (KAP): $850
  • Medical Consultations: $125–$400
  • Medical Evaluation for ketamine treatments: $250
  • IV Wellness Infusions: $150 – $250
  • Integration Therapy: $150–$175 per session

Package options and additional services are available, and our team is always available to walk through options with you. 

Payment for self-pay services is collected at check-in. We accept cash, check, credit and debit cards, HSA/FSA, and CareCredit, which offers flexible payment options.

Click here to find our detailed pricing information

Ketamine FAQs

  • IV Infusion – Gentle, fully monitored experience with real-time dose adjustments.
  • IM (Injection) – Quick, deeply immersive experience without an IV line.
  • Spravato® – FDA-approved nasal spray for treatment-resistant depression, typically covered by insurance.

Your physician will help you decide which route best fits your needs and goals.

  1. Schedule a medical evaluation by calling 651-280-8774.
  2. Activate your patient portal and complete all consent forms prior to your first appointment.
  3. Meet with one of our physicians to create your personalized plan of care.
  4. Begin treatment based on your personalized plan of care
    • IV or IM ketamine (without therapist): Treatments may be scheduled immediately.
    • Ketamine-Assisted Psychotherapy (KAP): Begin with 1–2 preparation sessions before scheduling treatment.
    • Spravato®: Scheduled after insurance prior authorization is approved and medication has arrived at IIT.
  5. Integrate your experience with ongoing support from your physician and integration therapists.

Most describe feelings of peace, clarity, and insight. You’ll relax with music, eyes covered, and supportive monitoring. Each journey is unique, and integration helps you carry insights into daily life.

Short-term effects may include mild dizziness, nausea, or temporary changes in perception or blood pressure. Our team monitors and manages these during your treatment to ensure safety.

Using insurance typically involves two parts to your investment:

  • Insurance responsibilities (co-pay, deductible, or co-insurance based on your plan).
  • Direct investment for non-covered services, collected at check-in.

Typical direct investment amounts:

  • IM Injection — $50 per injection, up to 3 injections
  • 1-Hour IV Infusion — $250
  • 2-Hour IV Infusion — $500
  • KAP (IM) — $500

Coverage varies by plan — please confirm benefits with your insurance provider before treatment.

Stay hydrated, avoid caffeine and food 4-hours prior, and arrange a ride home. Wear comfortable clothes and bring a journal if you wish to record insights. If you drink alcohol, it is recommended to avoid alcohol the day before your treatment and the following two weeks after.

Research FAQs

IIT regularly adds new clinical research trials as opportunities become available.

Please refer to our Clinical Research page to see if you meet eligibility criteria.
Click here to learn more about IIT’s clinical trials